Best APC2 antibody

Our APC2 Antibody is a rabbit polyclonal antibody raised against a synthetic peptide corresponding to the C-terminus of human APC2. Our APC2 Antibody has been validated for IHC, Peptide-ELISA and WB.

Activated protein C (APC) is an important hemostatic factor that regulates coagulation, endothelial barrier function, and inflammation. We previously engineered a high-affinity humanized chimeric antibody, SR604, that binds to human APC with a KD 60 times greater than Humab-14 and has prophylactic and therapeutic efficacy in mice with hemophilia A or B expressing human APC (humanized hemophilic mice) (Figure 3). Find out bosterbio.com

Best APC2 Antibody: How to Identify High-Quality Products

The cellular mechanisms of APC2 action are not fully understood. We recently reported that the cytoplasmic domain of APC2 is acetylated, and this acetylation is required for APC2 interaction with microtubules. We therefore examined whether APC2 overexpression alters microtubule dynamics by transfecting L cells and B103 cells with a control or APC2 expression plasmid, and then analyzing cell structures using anti-acetylated or anti-detyrosinated tubulin antibodies. Overexpression of APC2 significantly enhanced the colocalization of acetylated tubulin, and a 2.5-fold or 2-fold increase in the concentration of acetylated tubulin was observed when APC2 expression was increased.

We also performed ephrin-A2 stripe assays with control and APC2 knockdown nasal and temporal axons in cultured hippocampal neurons and found that both the control and APC2 knockdown axons avoided ephrin-A2-Fc stripes, but the APC2 shRNA-treated nasal axons did not (Fig. 7A). Nocodazole treatment, which disruptes microtubule stability, reduced the avoidance of ephrin-A2-Fc by both the control and APC2 knockdown nasal axons. The results suggest that APC2 functions as an MAP-like protein in neurons by stabilizing microtubules, and this function is essential for the normal response of retinal axons to a repulsive guidance molecule in the tectum.

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The right laptop for school strikes a balance between performance sufficient for most productivity tasks, affordability for student budgets, and durability to handle the kind of wear-and-tear that’s typical of college life. For most students, a laptop with mid-tier 13th Gen Intel Core CPUs or AMD Ryzen mobile processors will suffice. Best 14-inch laptops for Students can comfortably handle word processing, web browsing, streaming videos, and casual gaming – and they do so with respectable battery life.

Best 14 Inch Laptops for Students: Lightweight & Long Battery Life

To avoid having to search for power outlets during class or meetings, look for a model with a 70 Wh battery. This should last a full day with prudent use and have fast-charging capabilities, allowing it to charge from empty to 60% in an hour. A good laptop also comes with ports for USB-C, 3.5mm headphone, Kensington lock slot, and HDMI, and should have a solid display.

If you’re a fan of 2-in-1 convertible laptops, the HP Spectre x360 14 is the one to get. This laptop crushes expectations in every way, including battery life (a whopping 13 hours), stunning OLED display, powerful speakers, a satisfying keyboard, and a sleek design. Its only downfall is the lack of a bundled stylus, though Laptop Mag found that many people don’t need this feature.

If you’re on a tighter budget, the Lenovo IdeaPad Slim 3i Chromebook 14 (2023) offers comparable value to the HP Spectre x360 14. It’s configured with Intel’s Meteor Lake CPUs that are capable of handling most productivity workloads, and it can be specced with up to 64GB of RAM for demanding workloads. It’s available with either an FHD+ IPS or OLED display, but the OLED version has a lower resolution and 60Hz refresh rate and can cause screen flicker for those who are sensitive to it.…

Discounted Custom Blinds can be a stylish, functional, and relatively inexpensive way to refresh a room. But, until recently, it wasn’t a quick or easy process to order and install them. Shoppers were required to head to a home improvement store or specialty window covering center to meet with a design consultant, schedule a technician to come out and measure their windows, then wait weeks for the product.

That is no longer the case. Several online retailers have emerged with a variety of options, including customizable blinds and shades that can be ordered on the website and shipped directly to your house. We vetted the best online retailers for window coverings, comparing their selection, customization, and delivery/installation options, return policies, and more. We also spoke with Nicole Roe, a home designer and blogger at the Spruce, for shopping tips.

Wayfair

Wayfair is a go-to for home goods, including furniture and decor, so it’s no surprise that the retailer offers a vast selection of blinds and shades. The site has filters that make it easy to narrow down your search based on size, type, mounting location, light filtration, and materials. It’s also straightforward to find ratings and reviews for each product, so you can make a confident purchase. The site doesn’t offer professional installation, however, so you’ll need to enlist the help of a handy friend or hire a TaskRabbit. It does, however, offer free shipping and an easy-to-use compare function that allows shoppers to see the features of up to four products side-by-side.…